Open AccessBacterial cleavage of nitrogen to sulfone bonds in sulfamide and 1 H ‐2,1,3‐benzothiadiazin‐4(3 H )‐one 2,2‐dioxide: formation of 2‐nitrobenzamide by Gordonia sp.
Author(s) -
Rein Ulrike,
Cook Alasdair M.
Publication year - 1999
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1999.tb13457.x
Subject(s) - sulfamide , chemistry , sulfur , yield (engineering) , bacteria , strain (injury) , stereochemistry , nitrogen , nuclear chemistry , organic chemistry , materials science , biology , metallurgy , genetics , anatomy
Abstract Pure cultures of aerobic bacteria were isolated which could utilize sulfamate, sulfamide or 1 H ‐2,1,3‐benzothiadiazin‐4(3 H )‐one 2,2‐dioxide (BTDD) as sole source of sulfur for growth and thus cleave a N–S(O) x bond. The molar growth yields indicated that each source of sulfur was utilized quantitatively. This was confirmed directly for Gordonia sp. strain BT2 utilizing BTDD, which was converted quantitatively via an unidentified intermediate to 2‐nitrobenzamide. Another isolate, strain BT1, could utilize saccharin to yield salicylamide, thus cleaving both the N–S(O) x and C–S(O) x bonds.