Open AccessProduction of butyrolactone autoregulators by Streptomyces coelicolor A3(2)
Author(s) -
Kawabuchi Masahiro,
Hara Yoshitaka,
Nihira Takuya,
Yamada Yasuhiro
Publication year - 1997
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1997.tb12756.x
Subject(s) - streptomyces coelicolor , actinomycetales , streptomycetaceae , streptomyces , mycelium , biology , botany , bacteria , genetics
We report here that Streptomyces coelicolor A3(2) produces at least seven butyrolactone autoregulators: two of the IM‐2 type, four virginiae butanolide type, and one A‐factor type. The most abundant one corresponds to virginiae butanolide‐C 9 having a C2 side chain of nine carbons. Model butyrolactone compounds as well as extracts of S. coelicolor mycelia showed clear induction of morphological differentiation, implying that S. coelicolor A3(2) probably possessed butyrolactone‐type autoregulator(s) controlling the morphological differentiation.