Open AccessBovine attaching and effacing Escherichia coli possess a pathogenesis island related to the LEE of the human enteropathogenic Escherichia coli strain E2348/69
Author(s) -
Goffaux Frederic,
Mainil Jacques,
Pirson Vinciane,
Charlier Gerard,
Pohl Pierre,
Jacquemin Etienne,
China Bernard
Publication year - 1997
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1997.tb12676.x
Subject(s) - virulence , enteropathogenic escherichia coli , pathogenesis , escherichia coli , microbiology and biotechnology , biology , strain (injury) , diarrhea , enterobacteriaceae , virology , genetics , gene , medicine , immunology , anatomy
Attaching and effacing Escherichia coli (AEEC) has been described as a cause of diarrhea in calves. The molecular pathogenesis of AEEC was mainly studied in human enteropathogenic E. coli strain E2348/69 in which the virulence correlated with the presence of a 35.4 kb pathogenesis island called LEE. We showed that several strains isolated from calves with diarrhea were able to produce attaching and effacing lesions in a rabbit ileal loop model and that they possess a pathogenesis island related to the LEE. Moreover, we showed that the LEE from bovine strains was inserted mainly at a different position in the chromosome compared to the human enteropathogenic E. coli strain E2348/69.