Open AccessGlisoprenin A, an inhibitor of the signal transduction pathway leading to appressorium formation in germinating conidia of Magnaporthe grisea on hydrophobic surfaces
Author(s) -
Thines Eckhard,
Eilbert Frank,
Sterner Olov,
Anke Heidrun
Publication year - 1997
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1997.tb12573.x
Subject(s) - appressorium , magnaporthe grisea , conidium , biology , germination , microbiology and biotechnology , signal transduction , magnaporthe , adenosine , cyclic adenosine monophosphate , botany , biochemistry , receptor , oryza sativa , gene
Glisoprenin A, a fungal metabolite obtained from submerged cultures of Gliocladium roseum , interfered with appressorium formation in germinating conidiospores of Magnaporthe grisea on hydrophobic surfaces. In the absence of a hydrophobic surface, induction of appressorium formation by cAMP, 8,4‐chlorophenylthio‐adenosine‐3′,5′‐monophosphate, 3‐isobutyl‐1‐methylxanthine or 1,16‐hexadecanediol, a plant wax component, was not affected. When the chemical signals were tested on a hydrophobic surface, however, no formation of infectious structures was observed in the presence of glisoprenin A. The results indicate that in appressorium formation two signal transducing pathways are involved, which operate partly independently of each other.