Open AccessIsolation and characterization of a Listeria monocytogenes mutant strain hyperproducing virulence factors
Author(s) -
Ermolaeva Svetlana,
Varfolomeeva Nina,
Belyi Yuri,
Tartakovskii Igor
Publication year - 1997
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1997.tb10369.x
Subject(s) - listeria monocytogenes , virulence , mutant , strain (injury) , microbiology and biotechnology , biology , listeria , bacteria , virulence factor , isolation (microbiology) , biochemistry , gene , genetics , anatomy
A mutant strain characterized by hyperproduction of a number of cell wall and supernatant proteins was isolated after N ‐methyl‐ N ′‐nitro‐ N ‐nitrosoguanidine treatment of Listeria monocytogenes strain NCTC10527. Several of these proteins were identified as virulence factors. When a wild‐type strain was grown in the presence of activated charcoal it was shown to exhibit the same protein pattern as the isolated mutant.