Open AccessAbc1: a new ABC transporter from the fission yeast Schizosaccharomyces pombe
Author(s) -
Christensen Per U,
Davis Kevin,
Nielsen Olaf,
Davey John
Publication year - 1997
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1997.tb10226.x
Subject(s) - schizosaccharomyces pombe , yeast , gene , schizosaccharomyces , transmembrane protein , atp binding cassette transporter , fission , transporter , biology , sequence (biology) , genetics , chemistry , saccharomyces cerevisiae , receptor , physics , quantum mechanics , neutron
We have isolated the abc1 gene from the fission yeast Schizosaccharomyces pombe . Sequence analysis suggests that the Abc1 protein is a member of the ABC superfamily of transporters and is composed of two structurally homologous halves, each consisting of a hydrophobic region of six transmembrane domains and a hydrophilic region containing one ATP‐binding site. The abc1 gene appears to be expressed under all growth conditions but gene disruption experiments indicate that it is not essential for growth. The sequence of the abc1 gene has been deposited in the EMBL data library under the Accession Number Y09354.