Open AccessInhibitory effects of nucleoside 5′‐alkylphosphates on sexual agglutination in Saccharomyces cerevisiae
Author(s) -
Machida Kiyotaka,
Tanaka Toshio,
Shibata Kozo,
Taniguchi Makoto
Publication year - 1997
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1997.tb10214.x
Subject(s) - saccharomyces cerevisiae , nucleoside , inhibitory postsynaptic potential , agglutination (biology) , chemistry , biochemistry , biology , genetics , yeast , antibody , endocrinology
Among various nucleoside 5′‐alkylphosphates, uridine 5′‐hexadecylphosphate (UMPC16) and adenosine 5′‐hexadecylphosphate (AMPC16) inhibited the sexual agglutination between a and α haploid cells of Saccharomyces cerevisiae . The effect of AMPC16 accompanied severe growth inhibition of the yeast cells but it was not observed with UMPC16. Sexual agglutination was not inhibited by the presence of UMPC16 or AMPC16 when the yeast cells had been pretreated with the mating pheromone. UMPC16 was characterized as a specific inhibitor of sexual agglutination without direct influence on the agglutinin function, being distinguishable from any of those ever known.