Open AccessUtilization of acetonitrile and other aliphatic nitriles by a Candida famata strain
Author(s) -
Linardi Valter R.,
Dias João C.T.,
Rosa Carlos A.
Publication year - 1996
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1996.tb08510.x
Subject(s) - acetamide , propionitrile , acetonitrile , chemistry , nitrile hydratase , nitrile , acrylonitrile , amidase , hydrolysis , organic chemistry , copolymer , polymer
A variant of a yeast strain identified as Candida famata isolated from gold mine effluent was able to grow on acetonitrile, acrylonitrile, butyronitrile, isobutyronitrile, methacrylnitrile, propionitrile, succinonitrile, valeronitrile, acetamide, isobutyamide, and succinamide as sole nitrogen source, after acclimatization. The yeast grew on acetonitrile and acetamide at concentrations up to 4%. The utilisation of acetonitrile and acetamide by the C. famata strain probably involves hydrolysis in a two‐step reaction mediated by both inducible and intracellular nitrile hydratase and amidase.