Open AccessAutocrine response of Schizosaccharomyces pombe haploid cells to mating pheromones
Author(s) -
Kitamura Kenji,
Nakamura Tomohiro,
Miki Futaba,
Shimoda Chikashi
Publication year - 1996
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1996.tb08459.x
Subject(s) - schizosaccharomyces pombe , mating , sex pheromone , biology , mating of yeast , mating type , pheromone , zoology , microbiology and biotechnology , genetics , yeast , saccharomyces cerevisiae , gene
The mating response of the fission yeast Schizosaccharomyces pombe is mediated by mating pheromones, M‐factor and P‐factor, produced by h − and h + cells, respectively. When the M‐factor receptor (Map3) was ectopically expressed in h − cells lacking the P‐factor receptor (Mam2), they acquired mating competence in response to M‐factor which they secreted. The autocrine response to P‐factor in h + cells was so weak that mating competence was not acquired, although expression of the pheromone‐responsive gene mat1‐Pm was detected. These observations support the notion that the intensity of cellular response to mating pheromones is different between h − and h + cells, although downstream pathways of the pheromone receptors are shared by the two mating types.