Open AccessRole of ribosome degradation in the death of heat‐stressed Salmonella typhimurium
Author(s) -
TolkerNielsen Tim,
Molin Søren
Publication year - 1996
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1996.tb08423.x
Subject(s) - ribosome , ribosomal rna , salmonella , rna , programmed cell death , degradation (telecommunications) , 16s ribosomal rna , chemistry , microbiology and biotechnology , biology , biochemistry , bacteria , gene , apoptosis , genetics , telecommunications , computer science
Heat treatment of Salmonella typhimurium results in cell death, which coincides with a significant reduction of the cellular content of 16S ribosomal RNA. It is suggested that the degradation of ribosomal RNA is a direct cause of cell death. This conclusion is based on the observations of carbon‐starved and magnesium‐supplemented cells, which survive heat treatment much better, and which also maintain stable levels of ribosomal RNA.