Open AccessResponse of Mycobacterium smegmatis to acid stress
Author(s) -
O'brien Lyn M.,
Gordon Stephen V.,
Roberts Lan S.,
Andrew Peter W.
Publication year - 1996
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1996.tb08173.x
Subject(s) - mycobacterium smegmatis , microbiology and biotechnology , mycobacterium , adaptation (eye) , biology , bacteria , chemistry , biochemistry , genetics , medicine , mycobacterium tuberculosis , tuberculosis , pathology , neuroscience
Evidence was sought for the existence of an inducible acid tolerance response in Mycobacterium smegmatis . Exposure of M. smegmatis to a sub‐lethal, adaptive acidic pH was found to confer a significant level of protection against subsequent exposure to a lethal pH, compared to unadapted cells. Adaptation was dependent on de novo protein synthesis.