
Characterization of the smtA gene encoding an S‐adenosylmethionine‐dependent methyltransferase of Escherichia coli
Author(s) -
Yamanaka Kunitoshi,
Ogura Teru,
Niki Hironori,
Hiraga Sota
Publication year - 1995
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1995.tb07861.x
Subject(s) - escherichia coli , operon , gene , biology , microbiology and biotechnology , genetics , methyltransferase , methylation
The mukB operon is located at 21 min on the Escherichia coli chromosome and seems to consist of four genes, orf30 ( smtA ), mukF , mukE , and mukB . Based on sequence similarity, the promoter‐proximal gene, orf30 ( smtA ), could encode an S‐adenosylmethionine‐dependent methyltransferase. The smtA gene is not essential for cell growth and its expression is positively regulated by H‐NS, an Escherichia coli histone‐like protein.