Open AccessHeavy metal effects on Proteus mirabilis Superoxide dismutase production
Author(s) -
Eickhoff Jennifer,
Potts Elizabeth,
Valtos Joshua,
Niederhoffer Eric C.
Publication year - 1995
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1995.tb07845.x
Subject(s) - proteus mirabilis , superoxide dismutase , cadmium , dismutase , chemistry , proteus , metal , biochemistry , microbiology and biotechnology , food science , oxidative stress , biology , escherichia coli , organic chemistry , gene
Proteus mirabilis expressed three Superoxide dismutase activities, which depended on the level of soluble iron and dioxygen in the culture medium. Cadmium and lead decreased production of super oxide dismutase in liquid culture and on solid medium. A fourth super oxide dismutase activity appeared in extracts from cells grown in the presence of cadmium. These results support the idea of an interaction between toxic metal ions and putative iron‐ and redox‐dependent regulatory systems.