Open AccessComparison of Borrelia isolated from UK foci of Lyme disease
Author(s) -
Livesley M. Anne,
Thompson Ian P.,
Rainey Paul B.,
Nuttall Patricia A.
Publication year - 1995
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1995.tb07712.x
Subject(s) - spirochaete , lyme disease , borrelia , biology , borrelia burgdorferi , lyme borreliosis , plasmid , microbiology and biotechnology , restriction enzyme , virology , bacteria , genetics , gene , antibody
Restriction endonuclease digestion of linear borrelial chromosomal DNA showed that three isolates of UK Lyme disease spirochaetes differed markedly from each other and from published data for other isolates from North America and continental Europe. Analysis of linear plasmid bands revealed that UK isolates differed from each other in the number and sizes of the plasmids in isolates from different foci of UK Lyme disease. Fatty acid analysis (of fatty acid methyl ester (FAME) profiles) showed the UK isolates clustering together with the relapsing fever spirochaetes, Borrelia turicatae and Borrelia parkeri . These data are discussed in respect of current knowledge of Lyme borreliosis in the UK.