Open AccessSelection or mutation: Which, if either, comes first?
Author(s) -
Hall Barry G.
Publication year - 1994
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1994.tb06773.x
Subject(s) - selection (genetic algorithm) , mutation , biology , genetics , gene , computer science , artificial intelligence
Selection‐induced mutations (SIMS) are mutations that occur as specific and direct responses to environmental challenges, and that occur more often when they are selectively advantageous than when they are selectively neutral. This review includes discussions of how the occurrence of SIMS is measured, acquisitive evolution by SIMS, some of the controversies surrounding SIMS and models that have been advanced to explain the specificity of SIMS, and the requirement of a functional recA gene product for SIMS to occur.