
Toxic effect on human spermatozoa by Chlamydia trachomatis purified lipopolysaccharide
Author(s) -
Galdiero Francesco,
Sommese Linda,
Gorga Fernanda,
Galdiero Emilia,
Rizzo Antonietta,
Ajello Maria
Publication year - 1994
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1994.tb06637.x
Subject(s) - lipopolysaccharide , chlamydia trachomatis , incubation , microbiology and biotechnology , chlamydia , microgram , chlamydiaceae , chlamydiales , chemistry , andrology , biology , immunology , medicine , in vitro , biochemistry
We have investigated the effect that lipopolysaccharide extracted from Chlamydia trachomatis has on human spermatozoa. A lipopolysaccharide of 0.1 μg ml −1 caused a spermatozoa mortality rate of 65±4% evaluated by eosin exclusion test. The toxic activity occurred rapidly even after brief incubation times, reaching the maximum (100% mortality) within 60 min.