Open Access5‐Methoxyindole‐2‐carboxylic acid is a potent inhibitor of respiration and potassium ion transport in the archaebacterium Haloferax volcanii
Author(s) -
Meury Jean
Publication year - 1993
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1993.tb06114.x
Subject(s) - haloferax volcanii , respiration , biochemistry , metabolism , chemistry , cyanide , cellular respiration , biology , organic chemistry , gene , botany , archaea
5‐Methoxyindole‐2‐carboxylic acid strongly decreased respiration in the archaebacterium Haloferax volcanii , both in growing cells and in K + ‐depleted cells. It also inhibited the ability of depleted cells to take up K + , although the membrane potential δψ and the ATP pool were essentially maintained. Cyanide triggered a similar effect. These results suggest that respiration is a necessary condition for K + transport in H. volcanii .