Open AccessAlternate interactions of the d ‐galactose‐specific yeast lectin Kb‐CWL I with sensitive yeast strains
Author(s) -
Viard B.,
Streiblova E.,
Bonaly R.
Publication year - 1993
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1993.tb05997.x
Subject(s) - yeast , kluyveromyces lactis , lectin , biology , candida albicans , germ tube , kluyveromyces , candida tropicalis , biochemistry , microbiology and biotechnology , galactose , saccharomyces , rhodotorula , saccharomyces cerevisiae
In vitro growth assays with a purified d ‐galactose‐specific lectin Kb‐CWL I extracted from Kluyveromyces bulgaricus showed marked antifungal effects on 9 of 12 test strains belonging to the genera Kluyveromyces, Saccharomyces, Pichia, Candida, Rhodotorula and Schizosaccharomyces . The inhibition of growth was proportional to the lectin concentration (0.04 and 0.08 mg ml −1 ) in the culture medium. Under the test conditions, K. bulgaricus, K. lactis and S. bayanus were consistently agglutinated without growth inhibition. d ‐Galactose, the inhibitory sugar of the cell aggregation activity, did not abolish the antifungal effects of the lectin Kb‐CWL I on other yeast strains tested. In C. albicans and C. tropicalis , the lectin influenced the dimorphism of these strains and stimulated germ tube formation.