Open AccessEffect of host lineage on the virulence of Campylobacter jejuni/coli in the chick embryo model
Author(s) -
King Vicki,
Bavetsia Anita,
Bumstead Nat
Publication year - 1993
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1993.tb05975.x
Subject(s) - virulence , biology , campylobacter jejuni , microbiology and biotechnology , embryo , campylobacter , strain (injury) , lineage (genetic) , chorioallantoic membrane , host (biology) , inoculation , bacteria , virology , gene , genetics , immunology , anatomy
The chorioallantoic membrane (CAM) inoculated chick embryo model was used to study the effect of host lineage on the virulence of Campylobacter jejuni and Campylobacter coli . LD 50 values were used to compare the susceptibilities of chick embryos from eight inbred chicken lines to infection by four strains of C. jejuni and one strain of C. coli . Differences in susceptibility were found between inbred chicken lines. These were shown not to be due to maternal antibody status, not transfer of antibody to the developing embryo. Susceptibility to infection was also found to vary according to the Campylobacter strain used. These results indicate that both the bacterial strain and host lineage of the chicken line used affect resistance to infection in the CAM inoculated chick embryo model.