Open AccessFungal 17β‐hydroxysteroid dehydrogenase
Author(s) -
Lanišnik Tea,
ŽakeljMavrič Marija,
Belič Igor
Publication year - 1992
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1992.tb05540.x
Subject(s) - dehydrogenase , trichoderma viride , enzyme , hydroxysteroid dehydrogenase , oxidative enzyme , regioselectivity , steroid , hydroxysteroid dehydrogenases , oxidative phosphorylation , biology , biochemistry , hydroxysteroid , chemistry , microbiology and biotechnology , hormone , botany , catalysis
Two representatives of each of different fungal taxonomic classes were tested for constitutive 17β‐hydroxysteroid dehydrogenase (HSDH) activity and the results were positive in all cases. The enzyme was found to be regioselective for C 17 of the steroid ring and 20β‐HSDH activity was only detected in Trichoderma viride . In most cases the oxidative pathway is favoured over the reductive pathway. The possible role of this enzyme in fungi is discussed.