Open AccessSusceptibility of biofilm cells of Pseudomonas aeruginosa to bactericidal actions of whole blood and serum
Author(s) -
Anwar Hosmin,
Strap Janice L.,
William Costerton J.
Publication year - 1992
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1992.tb05267.x
Subject(s) - biofilm , pseudomonas aeruginosa , microbiology and biotechnology , organism , biology , persistence (discontinuity) , pseudomonas , whole blood , bacteria , immunology , paleontology , genetics , geotechnical engineering , engineering
The planktonic and young biofilm cells (harvested on day 2) of mucoid Pseudomonas aeruginosa were susceptible to the bactericidal actions of whole blood and serum. Aging biofilms of this organism (harvested on day 7) were very resistant to the killing effect of whole blood and serum. From this study we propose that the establishment of aging biofilms may contribute to persistence of this organism in biofilm‐associated infections.