Open AccessCyclic diguanylic acid stimulates 1,4‐μ‐glucan synthase from Saprolegnia monoica
Author(s) -
Girard Vincent,
Fevre Michel,
Mayer Raphaël,
Benziman Moshe
Publication year - 1991
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1991.tb04897.x
Subject(s) - atp synthase , activator (genetics) , biochemistry , enzyme , glucan , biology , chemistry , microbiology and biotechnology , gene
1,4‐μ‐Glucan synthase activity, but not 1,3‐μ‐glucan‐synthase activity, from Saprolegnia monoica was stimulated by cyclic‐diguanylic acid, an immediate activator of Acetobacter xylinum ‐ cellulose synthase. This activator, which increased the V max without modifying the K m for UDP‐glucose, was active on solubilized and partially purified enzymes. These results suggest that the fungal system shares a common regulatory mechanism with the bacterial system.