Open AccessDemonstration of formaldehyde dehydrogenase activity in formaldehyde‐resistant Enterobacteriaceae
Author(s) -
Kaulfers PaulMichael,
Marquardt Annette
Publication year - 1991
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1991.tb04551.x
Subject(s) - formaldehyde dehydrogenase , formaldehyde , disinfectant , enterobacteriaceae , chemistry , glutathione , microbiology and biotechnology , enzyme , biochemistry , dehydrogenase , biology , escherichia coli , organic chemistry , gene
Summary Clinical isolates of different Enterobacteriaceae strains and genetically modified variants which were resistant to the disinfectant formaldehyde were investigated. In cell‐free extracts of all formaldehyde‐resistant strains a glutathione‐dependent formaldehyde dehydrogenase activity was demonstrated. In contrast cell extracts from formaldehyde‐sensitive strains did not show any formaldehyde dehydrogenase activity. The enzymatic degradation of formaldehyde seems to play an important role in formaldehyde resistance.