Open Accessδ‐like haemolysin produced by Staphylococcus lugdunensis
Author(s) -
Vandenesch François,
Storrs Michèle J.,
PoitevinLater Françoise,
Etienne Jérôme,
Courvalin Patrice,
Fleurette Jean
Publication year - 1991
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1991.tb04418.x
Subject(s) - staphylococcus lugdunensis , microbiology and biotechnology , hemolysin , staphylococcus , staphylococcus aureus , biology , bacteria , virulence , genetics , gene
Summary Thirty independent clinical isolates of Staphylococcus lugdunensis were tested for expression of haemolysin characteristics of Staphylococcus aureus and for the presence of DNA sequences with homology to S. aureus toxin genes. Twenty‐six strains produced a thermostable haemolysin with greatest activity against rabbit erythrocytes. DNA‐DNA hybridisation was performed with S. lugdunensis DNA and probed with the α, β, δ and γ toxin gene probes of S. aureus as well as that for coagulase. Hybridisation was found with the δ probe in 28 strains including 6 which did not express haemolysin. Two strains did not hybridise with any of the probes. These findings suggest that S. lugdenensis strains produce a δ‐like toxin which shares homology with the δ toxin of S. aureus .