Open AccessInactivation of T5 phage by cis ‐vaccenic acid, an antivirus substance from Rhodopseudomonas capsulata , and by unsaturated fatty acids and related alcohols
Author(s) -
Hirotani H.,
Ohigashi H.,
Kobayashi M.,
Koshimizu K.,
Takahashi E.
Publication year - 1991
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1991.tb04314.x
Subject(s) - oleic acid , chemistry , fatty acid , alcohol , chromatography , mass spectrometry , unsaturated fatty acid , gas chromatography–mass spectrometry , biochemistry
Summary The antiviral extract from Rhodopseudomonas capsulata was purified and the predominant active component was defined as cis ‐vaccenic acid (C1‐ 8:1 Δ11) by gas‐liquid chromatography and gas chromatography‐mass spectrometry analyses. Antiviral activities of unsaturated fatty acids and related alcohols against T5 phage were also tested. Among them, linoelaidic acid, oleic acid, and petroselenyl alcohol inactivated 98%, 53%, 67% of T5 phage at the concentration of 50 μ g/ml, respectively.