Open AccessIn vitro adrenalin oxidation, in bacteriological media, causes bacterial growth inhibition and killing
Author(s) -
Giunta Sergio,
Galeazzi Luciano,
Turchetti Gianni,
Grilli Giordano,
Groppa Giuseppe
Publication year - 1990
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1990.tb13829.x
Subject(s) - catalase , superoxide dismutase , autoxidation , toxicity , bacterial growth , microbiology and biotechnology , in vitro , bacteria , enzyme , chemistry , growth inhibition , biochemistry , oxygen toxicity , biology , oxygen , organic chemistry , genetics
We present experimental evidence that adrenalin autoxidation causes bacterial growth inhibition and killing. The experimental model utilized detects ‘oxygen toxicity’ in prokaryotes using standard microbiological assays for antibacterial activity, allowing direct observation of the toxicity exerted on bacterial cells and the scavenging of toxic intermediates by the defence enzymes catalase and superoxide dismutase.