Open AccessDihydroxybenzolyserine—a siderophore for E. coli
Author(s) -
Hantke Klaus
Publication year - 1990
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1990.tb13826.x
Subject(s) - siderophore , escherichia coli , bacterial outer membrane , cytoplasm , enterobacteriaceae , biochemistry , biology , chemistry , receptor , microbiology and biotechnology , gene
Dihydroxybenzoylserine, the breakdown product of enterochelin, was able to stimulate growth of Escherichia coli under iron limiting conditions by acting as a siderophore. The dihydroxybenzoylserine‐iron complex was taken up via the outer membrane receptor proteins Fiu, FepA and to a minor extent via Cir. Transport fo Fe 3+ ‐dihydroxybenzoylserine across the cytoplasmic membrane was only dependent on genes from the fep region. In addition, it was shown that dihydroxybenzoate was taken up via Fiu and Cir and less efficiently by FepA.