
Formyl‐methanofuran synthesis in Methanobacterium thermoautotrophicum
Author(s) -
Bobik Thomas A.,
DiMarco Anthony A.,
Wolfe Ralph S.
Publication year - 1990
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1990.tb04931.x
Subject(s) - methanobacterium , chemistry , microbiology and biotechnology , biology , biochemistry , archaea , gene
The initial step of methanogenesis from CO 2 is the formation of formyl‐methanofuran (formyl‐MFR) from methanofuran (MFR), CO 2 and H 2 . The enzymology of this novel type of CO 2 fixation reaction has been difficult to study because formyl‐MFR synthesis is subject to a complex activation. Recently, however, a number of advances have made questions regarding formyl‐MFR synthesis more approachable.