Open AccessAntifungal drugs effect adherence of Candida albicans to acrylic surfaces by changing the zeta‐potential of fungal cells
Author(s) -
Miyake Yoichiro,
Tsunoda Tatsuhiko,
Minagi Shogo,
Akagawa Yasumasa,
Tsuru Hiromichi,
Suginaka Hidekazu
Publication year - 1990
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1990.tb04231.x
Subject(s) - zeta potential , candida albicans , antifungal , microbiology and biotechnology , corpus albicans , chemistry , biology , materials science , nanotechnology , nanoparticle
The effect of sub‐inhibitory concentrations of antifungal drugs on the adherence of Candida albicans to acrylic surfaces was investigated. Among five antifungals tested, azalomycin F and aculeacin A significantly enhanced the adherence. The zeta‐potential of fungal cells was affected by antifungal drugs, whereas no significant change in cell surface hydrophobicity was observed. The relationship obtained between the change in the adherence and that in zeta‐potential suggests that the enhanced adherence was caused by decreased electric repulsive forces.