Open AccessComplete nucleotide sequence of the sr gene from Streptococcus mutans OMZ 175
Author(s) -
Ogier J.A.,
Scholler M.,
Leproivre Y.,
Pini A.,
Sommer P.,
Klein J.P.
Publication year - 1990
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1990.tb04153.x
Subject(s) - peptide sequence , amino acid , nucleic acid sequence , nucleotide , sequence (biology) , biology , biochemistry , gene , streptococcus mutans , protein sequencing , genetics , chemistry , microbiology and biotechnology , bacteria
The nucleotide sequence encoding the SR protein of Streptococcus mutans OMZ 175 (serotype f) has been determined. The sr gene consists of 4667 bp and code for a 171177 Da protein. Comparison of the inferred amino acid sequence with the one of PAc antigen from S. mutans MT 8148 (serotype c) indicates a 88% conservation of amino acid residues which reflects the close relatedness of both proteins. Major differences in amino acid composition are located at the C‐terminal part of the sequence where only 298 amino acids of the terminal 420 are conserved.