Open AccessElimination of ColE 1 (pBR322 and pBR329) plasmids in Escherichia coli by α‐santonin
Author(s) -
Bharathi A.,
Polasa H.
Publication year - 1990
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1990.tb04151.x
Subject(s) - cole1 , plasmid , escherichia coli , pbr322 , biology , chemistry , microbiology and biotechnology , genetics , dna , gene
α‐Santonin, a compound extracted from the flower heads of Arthemisia maritima plant, was effective in elimination of small, multicopy, relaxed plasmids (pBR322 and pBR329 with CoLE 1 origin of replication in Escherichia coli , whereas plasmids of IncF 1 , H 1 and X group were totally refractory under similar conditions, suggesting that this agent was specific in curing the CoLE 1 group of plasmids.