Open AccessCo‐ordinated expression of the components of iron transport (mycobactin, exochelin and envelope proteins) in Mycobacterium neoaurum
Author(s) -
Sritharan Manjula,
Ratledge Colin
Publication year - 1989
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1989.tb03442.x
Subject(s) - envelope (radar) , chemistry , microbiology and biotechnology , biophysics , biology , computer science , telecommunications , radar
Mycobacterium neoaurum was grown with a range of iron concentrations from 0.01 to 4.0 μg/ml. Synthesis of the extracellular siderophore, exochelin, the intracellular iron storage compound, mycobactin and the iron‐repressible envelope proteins were co‐ordinately expressed. All three components of the iron transport system were synthesized when low amounts of iron (0.01 to 0.2 μg/ml) were added to the medium and were repressed when the iron concentration was increased to 0.5 μg/ml and above. These results re‐inforce the conclusion that the iron‐regulated proteins do fulfil an essential function in iron metabolism.