Open AccessIsolation and study of two mutants of Streptomyces cattleya affected in DNA repair and genetic instability
Author(s) -
Hromic Alma,
Kirby Ralph
Publication year - 1989
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1989.tb03288.x
Subject(s) - mutant , biology , streptomyces , dna , dna repair , isolation (microbiology) , genetics , genome instability , microbiology and biotechnology , dna damage , gene , bacteria
Two mutants of Streptomyces cattleya affecting DNA repair were isolated. These mutants were analysed using spore survival curves and phage reactivation curves in the presence and absence of caffeine and arsenite. Two DNA repair systems ( uvr 1 and uvr 2) were identified, the latter of which seems to influence genetic instability.