Open AccessTransfer of low level trimethoprim resistance in faecal isolates obtained from apparently healthy Nigerian students
Author(s) -
Lamikanra A.,
Fayinka Susan T.,
Olusanya O.O.
Publication year - 1989
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1989.tb03124.x
Subject(s) - trimethoprim , microbiology and biotechnology , biology , antibiotics , sulfamethoxazole , bacteria , enterobacteriaceae , antibiotic resistance , escherichia coli , genetics , gene
Twenty‐four of 63 enteric Gram‐negative organisms (38.1%) which were isolated from 35 apparently healthy Nigerian students were found to have low trimethoprim resistance (MIC < 1000 mg/1). These isolates were also found to be resistant to several other antibiotics and trimothoprim resistance was found to be transferable from 15 (62.5%) of the trimethoprim resistant organisms into E. coli EC 1005. It is likely that the high percentage of trimethoprim resistance encountered in this study is related to the high rate of resistance transfer which was observed.