Open AccessHomologues of catalytic domains of Cellulomonas glucanases found in fungal and Bacillus glycosidases
Author(s) -
West Catherine A.,
Elzanowski Andrzej,
Yeh LaiSu,
Barker Wia C.
Publication year - 1989
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1989.tb03103.x
Subject(s) - trichoderma reesei , cellulase , glycoside hydrolase , chemistry , microbiology and biotechnology , enzyme , glucan , biochemistry , stereochemistry , biology
We demonstrate homology between the catalytic domains of exoglucanase (1,4‐beta‐ d ‐glucan cellobiohydrolase, EC 3.2.1.91) from Cellulomonas fimi and those of endoxylanases (1,4‐beta‐ d ‐xylan xylanohydrolases, EC 3.2.1.8) from Bacillus sp. strain C‐125 and the fungus Cryptococcus albidus ; and between the catalytic domains of endoglucanase, (1,4‐(1,3: 1,4)‐beta‐ d ‐glucan 4‐glucanohydrolase, EC 3.2.1.4) from Cellulomonas fimi and exoglucanase II from Trichoderma reesei . These five enzymes apparently evolved by reshuffling of two catalytic domains and several substrate‐binding domains.