Open AccessChanges in fatty acid composition associated with differentiation of Trypanosoma cruzi
Author(s) -
Esteves Manuel G.,
GonzalesPerdomo Magaly,
Alviano Celuta S.,
Angluster Jayme,
Goldenberg Samuel
Publication year - 1989
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1989.tb03077.x
Subject(s) - trypanosoma cruzi , incubation , composition (language) , transformation (genetics) , biochemistry , biology , fatty acid , chemistry , chromatography , parasite hosting , gene , linguistics , philosophy , world wide web , computer science
The fatty acid composition during the transformation of Trypanosoma cruzi epimastigotes into metacyclic trypomastigotes (metacyclogenesis) was analysed by gas‐liquid chromatography and mass spectrometry. Significant qualitative and quantitative changes in the fatty acid composition occurred during incubation of epimastigotes derived from LIT medium in the triatomine artificial urine (TAU). Metacyclogenesis was also followed by alterations in the fatty acid pattern but these were considerably less pronounced when compared to the pattern obtained for TAU‐incubated epimastigotes. These results suggest that changes in the lipid composition precede the morphological transformation of epimastigotes into metacyclic trypomastigotes.