Open AccessLewis a blood group antigen of non‐secretors: a receptor for candida blastospores
Author(s) -
May S.J.,
Blackwell C.C.,
Weir D.M.
Publication year - 1989
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1989.tb02429.x
Subject(s) - receptor , antigen , yeast , antiserum , blood group antigens , biology , microbiology and biotechnology , chemistry , immunology , biochemistry
This study tested the hypothesis that the Lewis a blood group antigen found predominantly on the cells of non‐secretors might be one of the receptors for Candida species. Binding of strain 3118C to epithelial cells from either secretor or non‐secretor donors was not inhibited by treating the cells with anti‐Lewis a or anti‐Lewis b antisera. Binding of strain 3091 to non‐secretor cell was inhibited by pretreating the cells with anti‐Lewis a , but this was not observed for secretor cells. The results suggest that Lewis a might be one of the receptors for some yeast strains.