Open Accessβ‐Methylmuconolactone, a key intermediate in the dissimilation of methylaromatic compounds by a modified 3‐oxoadipate pathway evolved in nocardioform actinomycetes
Author(s) -
Bruce Neil C.,
Cain Ronald B.
Publication year - 1988
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1988.tb02944.x
Subject(s) - rhodococcus rhodochrous , rhodococcus , chemistry , stereochemistry , enzyme , biochemistry
p ‐Toluate‐grown cells of Rhodococcus ruber N75, R. corallinus N657, R. rhodochrous N5 and Rhodococcus strains BCN1, BCN2 and 4PH1 metabolized 4‐methylcatechol by a modified 3‐oxoadipate pathway. Steps in the conversion of this compound to 4‐methyl‐3‐oxoadipic acid were investigated. The conversion of 4‐carboxymethyl‐3‐methylbut‐2‐en‐1, 4‐olide to 4‐carboxymethyl‐3‐methylbut‐2‐en‐1, 4‐olide by a new enzyme is described.