Open AccessHow is nitrogenase regulated by oxygen?
Author(s) -
Hill Susan
Publication year - 1988
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1988.tb02738.x
Subject(s) - nitrogenase , catabolism , mechanism (biology) , enzyme , biochemistry , oxygen , substrate (aquarium) , cellular respiration , chemistry , metabolism , biology , nitrogen fixation , ecology , bacteria , genetics , philosophy , organic chemistry , epistemology , mitochondrion
Oxygen can be either beneficial or detrimental for diazotrophy in organisms capable of an aerobic catabolism. It supports the production of a substrate for nitrogenase (ATP), but it can also inhibit the activity and repress the synthesis of this enzyme. Here, aspects of the relevant physiology are reviewed with particular emphasis on those relating to the mechanism of O 2 regulation of nitrogenase synthesis.