Open AccessMutants of Spirulina platensis resistant to valine inhibition
Author(s) -
Riccardi Giovanna,
Rossi Edda,
Milano A.,
Felice Maurilio
Publication year - 1988
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1988.tb02675.x
Subject(s) - valine , spirulina (dietary supplement) , mutant , enzyme , biochemistry , biosynthesis , biology , chemistry , amino acid , microbiology and biotechnology , gene , raw material , ecology
Growth of the cyanobacterium Spirulina platensis is inhibited by low concentrations of valine. Spontaneous valine‐resistant mutants were isolated from S. platensis and a preliminary characterization of three of them indicates that one (strains DR2) is defective in valine uptake and two (strains DR5 and DR9) carry alterations in a valine‐mediated mechanism of synthesis of acetohydroxy acid synthase, the first common enzyme of the pathway.