Open AccessIron‐regulated synthesis and uptake of colicin V
Author(s) -
Chehade Heidi,
Braun Volkmar
Publication year - 1988
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1988.tb02591.x
Subject(s) - colicin , escherichia coli , repressor , bacterial outer membrane , mutant , plasmid , virulence , biology , gene , microbiology and biotechnology , enterobacteriaceae , chemistry , biochemistry , gene expression
Virulent strains of Escherichia coli frequently contain ColV plasmids. It is shown that synthesis of the marker protein, colicin V, is regulated by iron via the iron repressor encoded by the fur gene. Mutants in the Cir outer membrane protein, in tonB , as well as in the exbB gene are resistant to colicin V suggesting all three functions to be required for colicin V uptake.