Open AccessA highly conserved 530 base‐pair repeated DNA sequence specific for Bordetella pertussis
Author(s) -
Park Insoo,
Saurin William,
Ullmann Agnes
Publication year - 1988
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1988.tb02565.x
Subject(s) - bordetella pertussis , nucleic acid sequence , biology , genome , genetics , sequence (biology) , dna , virulence , dna sequencing , repeated sequence , bordetella , whooping cough , whole genome sequencing , base pair , conserved sequence , pertussis toxin , consensus sequence , microbiology and biotechnology , gene , bacteria , virology , base sequence , g protein , vaccination , receptor
The genome of Bordetella pertussis contains a strictly conserved 530 base‐pair (bp) repeated sequence present in about 70 to 80 copies and accounting for approximately 1% of the bacterial genome. The repeated element, whose complete nucleotide sequence has been determined, is specific for B. pertussis DNA; it could be detected neither in closely related Bordetella strains nor in other bacterial or eukaryotic DNAs. The repeated sequence is not associated with the control of the expression of virulence determinants.