Open AccessPromoting effects of 105K glycoprotein on cell proliferation in chicken lymphoblastoid cell lines
Author(s) -
Kotomura N.,
Matsuda H.,
Murata M.,
Matsumura K.
Publication year - 1988
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1988.tb02364.x
Subject(s) - glycoprotein , cell culture , lymphoblast , cell growth , microbiology and biotechnology , cell , biology , chemistry , virology , biochemistry , genetics
The promoting effects on cell proliferation of the 105K glycoprotein (105Kgp), purified from sera of chickens to which a Marek's disease (MD) lymphoblastoid cell line, MDCC‐MSB1‐41C (MSB1‐41C), had been transplanted, were examined using culture cells from various sources. The MSB1‐41C line as well as the other chicken lymphoblastoid cell lines examined were sensitive to the 105Kgp. The growth‐promoting effects of 105Kgp showed a biphasic pattern depending upon the amount of 105Kgp added into the culture medium. These findings indicate that the 105Kgp may be a promoting factor for chicken growing cells, especially lymphoblastoid cell lines.