Open AccessDispersion of a gene that codifies fosfomycin resistance among plasmids from enterobacteriaceae isolated from sewage
Author(s) -
Alvarez Ana M.,
Hardisson Carlos,
Mendoza M.Carmen
Publication year - 1987
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1987.tb02623.x
Subject(s) - plasmid , fosfomycin , replicon , enterobacteriaceae , biology , microbiology and biotechnology , genetics , bacteria , gene , escherichia coli , antibiotics
The presence of plasmid encoded resistance to fostomycin among enterobacteriaceae isolated from sewage was studied. These plasmids found were classified into 7 varieties according to their original host, size, resistance determinants, restriction pattern and incompatibility group. All of them were related to the Inc M group, indicating a probable common origin from an ancestral replicon. The bacteria carrying these plasmids modified fosfomycin as did those carrying fosfomycin resistant (Fo r ) hospital plasmids. The plasmids showed positive hybridization with a 1‐kb DNA fragment which carried a Fo r ‐determinant from a hospital plasmid.