Open AccessDecreased cupric ion uptake as the mechanism for cupric ion resistance in Escherichia coli
Author(s) -
Cotter C.M.,
Trevors J.T.,
Gadd G.M.
Publication year - 1987
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1987.tb02613.x
Subject(s) - escherichia coli , plasmid , kanamycin , strain (injury) , microbiology and biotechnology , chemistry , copper , enterobacteriaceae , bacteria , ion , biology , biochemistry , genetics , antibiotics , gene , organic chemistry , anatomy
Plasmid‐encoded copper (Cu 2+ ) resistance in Escherichia coli was due to decreased uptake of Cu 2+ . The Cu 2+ ‐resistant E. coli Rtsl strain contained a 60 MDa plasmid which is known to encode for both Cu 2+ and kanamycin resistance. A plasmid‐free derivative of the same organism exhibited a greater uptake of Cu 2+ , and sensitivity to Cu 2+ in both respiration and growth studies than the E. coli Rtsl strain.