Open AccessCommon antigenic determinants of pneumococcal penicillin‐binding protein (PBP) 1a and Streptococcus pyogenes PBP 2
Author(s) -
Hakenbeck Regine,
Ellerbrok Heinz,
Tornette Spassena,
Rijn Ivo
Publication year - 1987
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1987.tb02536.x
Subject(s) - streptococcus pneumoniae , streptococcus pyogenes , microbiology and biotechnology , penicillin binding proteins , antiserum , streptococcaceae , penicillin , biology , antigen , immunoprecipitation , streptococcus , bacteria , antibiotics , antibody , staphylococcus aureus , immunology , genetics
Antisera raised against penicillin‐binding protein (PBP) 1a of Streptococcus pneumoniae reacted with PBP 2 in certain strains of Streptococcus pyogenes . Cross‐reactivity could be demonstrated on immunoblots as well as by immunoprecipitation of native solubilised proteins, indicating a similar structural arrangement also in the native form of the two PBPs.