Open AccessProduction of neuraminidase by Micromonospora viridifaciens
Author(s) -
Aisaka Kazuo,
Uwajima Takayuki
Publication year - 1987
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1987.tb02284.x
Subject(s) - neuraminidase , micromonospora , glycosidic bond , microbiology and biotechnology , enzyme , biochemistry , microorganism , chemistry , bacteria , biology , streptomyces , genetics
A range of microorganisms were screened for new and high producer strains of neuraminidase (EC 3.2.1.18). High neuraminidase activity was found in the culture filtrates of Actinomycetes of the genus Micromonospora , and Micromonospora viridifaciens showed the highest enzyme activity. Neuraminidase production by M. viridifaciens was highly induced by the presence of the substrate colominic acid and the product N ‐acetylneuraminic acid. The purified neuraminidase of M. viridifaciens could cleave α(2–3), α(2–6), and α(2–8) glycosidic linkages.