
Inhibition of mutans streptococci by the hematin formed on blood‐containing media by proteolytic enterococci
Author(s) -
James Susan M.,
Tagg John R.
Publication year - 1987
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1987.tb02250.x
Subject(s) - microbiology and biotechnology , enterococcus faecalis , protease , incubation , agar , enterococcus , proteolytic enzymes , hemoglobin , chemistry , biology , agar plate , antagonism , bacteria , staphylococcus aureus , biochemistry , enzyme , antibiotics , genetics , receptor
Proteolytic Enterococcus faecalis isolates produced strong inhibitory activity against mutans streptococci in a deferred antagonism test on Columbia agar base medium supplemented with 5% human blood. Hematin was responsible for this inhibitory effect and its formation by the enterococci was dependent upon incubation in the presence of hemoglobin under conditions favourable to protease production.