Open AccessRepression of porin synthesis by salicylate in Escherichia coli, Klebsiella pneumoniae and Serratia marcescens
Author(s) -
Sawai Tetsuo,
Hirano Shinya,
Yamaguchi Akihito
Publication year - 1987
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1987.tb02031.x
Subject(s) - porin , serratia marcescens , klebsiella pneumoniae , microbiology and biotechnology , escherichia coli , mutant , enterobacteriaceae , biology , biochemistry , chemistry , bacterial outer membrane , gene
The synthesis of the OmpF porin in Escherichia coli K‐12 was highly and reversibly inhibited by 5 mM salicylate in the bacterial growth medium, and salicylate also inhibited the OmpC porin synthesis, although only weakly. The full expression of the salicylate effect was presumed to require the ompB gene product on comparison between the wild type and ompB mutant strains. The salicylate effect was also observed for the porin protein synthesis in Klebsiella pneumoniae and Serratia marcescens, although an ompB ‐like gene remains to be identified in both species.