Open AccessAdenylate pool sizes and succinate dehydrogenase activity increase continuously throughout the cell cycle of Escherichia coli
Author(s) -
Misri Ravinder,
Poole Robert K.
Publication year - 1986
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1986.tb01828.x
Subject(s) - escherichia coli , adenylate kinase , succinate dehydrogenase , exponential growth , cell cycle , biology , dehydrogenase , biochemistry , metabolism , cell , chemistry , microbiology and biotechnology , enzyme , gene , physics , quantum mechanics
In synchronous cultures of Escherichia coli , the pool sizes of ATP and ADP increase continuously, probably exponentially, such that the ATP/ADP ratio is invariant during the cell cycle. Resolution of cells from an exponentially growing culture into size, and thus age, classes reveals no significant variation in succinate dehydrogenase activity during the cell cycle. These data reinforce earlier findings that respiratory metabolism in the E. coli cell cycle is not manifestly periodic.